diff --git a/docs/full-configuration.md b/docs/full-configuration.md
index 4fffa5a7..6a1e4356 100644
--- a/docs/full-configuration.md
+++ b/docs/full-configuration.md
@@ -114,7 +114,7 @@ The configuration file contains the following sections:
 <details><summary><font size=4>ACME</font></summary>
 
 - **"acme"**, Automatic Certificate Management Environment (ACME) protocol configuration. To obtain the certificates the first time you have to configure the ACME protocol and execute the `sftpgo acme run` command. The SFTPGo service will take care of the automatic renewal of certificates for the configured domains.
-  - `domains`, list of domains for which to obtain certificates. If a single certificate is to be valid for multiple domains specify the names separated by commas, for example: `example.com,www.example.com`. An empty list means that ACME protocol is disabled. Default: empty.
+  - `domains`, list of domains for which to obtain certificates. If a single certificate is to be valid for multiple domains specify the names separated by commas or spaces, for example: `example.com,www.example.com` or `example.com www.example.com`. An empty list means that ACME protocol is disabled. Default: empty.
   - `email`, string. Email used for registration and recovery contact. Default: empty.
   - `key_type`, string. Key type to use for private keys. Supported values: `2048` (RSA 2048), `4096` (RSA 4096), `8192` (RSA 8192), `P256` (EC 256), `P384` (EC 384). Default: `4096`
   - `certs_path`, string. Directory, absolute or relative to the configuration directory, to use for storing certificates and related data.
diff --git a/internal/acme/acme.go b/internal/acme/acme.go
index 57667020..dd4caddb 100644
--- a/internal/acme/acme.go
+++ b/internal/acme/acme.go
@@ -489,14 +489,7 @@ func (c *Configuration) tryRecoverRegistration(privateKey crypto.PrivateKey) (*r
 }
 
 func (c *Configuration) obtainAndSaveCertificate(client *lego.Client, domain string) error {
-	var domains []string
-
-	for _, d := range strings.Split(domain, ",") {
-		d = strings.TrimSpace(d)
-		if d != "" {
-			domains = append(domains, d)
-		}
-	}
+	domains := getDomains(domain)
 	acmeLog(logger.LevelInfo, "requesting certificates for domains %+v", domains)
 	request := certificate.ObtainRequest{
 		Domains:                        domains,
@@ -655,8 +648,25 @@ func isDomainValid(domain string) (string, bool) {
 	return domain, isValid
 }
 
+func getDomains(domain string) []string {
+	var domains []string
+
+	delimiter := ","
+	if !strings.Contains(domain, ",") && strings.Contains(domain, " ") {
+		delimiter = " "
+	}
+
+	for _, d := range strings.Split(domain, delimiter) {
+		d = strings.TrimSpace(d)
+		if d != "" {
+			domains = append(domains, d)
+		}
+	}
+	return domains
+}
+
 func sanitizedDomain(domain string) string {
-	return strings.NewReplacer(":", "_", "*", "_", ",", "_").Replace(domain)
+	return strings.NewReplacer(":", "_", "*", "_", ",", "_", " ", "_").Replace(domain)
 }
 
 func stopScheduler() {